Dr. Soliman Alasaqaby
Research Interest
1. Molecular Medicine
2. Molecular Pathology of Cancer, Hematological Disorders, Neurodegenerative Diseases and Microbial Infection
3. Computational Biology and Bioinformatics
Publications
|
1. Alharbi, N.K., Al-Tawfiq, J.A., Alghnam, S., Alwehaibe, A., Alasmari, A., Alsagaby, S.A., Alotaibi, F., Alsubaie, F., Alshomrani, M., Farahat, F.M. and Bosaeed, M., 2022. Outcomes of Single Dose COVID-19 Vaccines: Eight Month Follow-up of a Large Cohort in Saudi Arabia. Journal of infection and public health Outcomes of Single Dose COVID-19 Vaccines: Eight Month Follow-up of a Large Cohort in Saudi Arabia |
|
2. Bijani, S., Iqbal, D., Mirza, S., Jain, V., Jahan, S., Alsaweed, M., Madkhali, Y., Alsagaby, S.A., Banawas, S., Algarni, A. and Alrumaihi, F., 2022. Green Synthesis and Anticancer Potential of 1, 4-Dihydropyridines-Based Triazole Derivatives: In Silico and In Vitro Study. Life, 12(4), p.519. |
|
3. Anwar, S., DasGupta, D., Azum, N., Alfaifi, S.Y., Asiri, A.M., Alhumaydhi, F.A., Alsagaby, S.A., Sharaf, S.E., Shahwan, M. and Hassan, M.I., 2022. Inhibition of PDK3 by artemisinin, a repurposed antimalarial drug in cancer therapy. Journal of Molecular Liquids, p.118928. Inhibition of PDK3 by artemisinin, a repurposed antimalarial drug in cancer therapy |
|
4. Khan, M.S., Shahwan, M., Shamsi, A., Alhumaydhi, F.A., Alsagaby, S.A., Al Abdulmonem, W., Abdullaev, B. and Yadav, D.K., 2022. Elucidating the Interactions of Fluoxetine with Human Transferrin Employing Spectroscopic, Calorimetric, and In Silico Approaches: Implications of a Potent Alzheimer’s Drug. ACS omega, 7(10), p.9015. |
|
5. Alsagaby, S., Ahmed, A.A., Rasheed, Z., Althwab, S.A., Aljohani, A.S., Alhumaydhi, F.A., Alhomaidan, H.T., Alkhamiss, A.S., Alkhowailed, M., Alaqeel, A. and Alblihed, M.A., 2022. Association of genetic polymorphisms in DNA repair genes ERCC2 Asp312Asn (rs1799793), ERCC2 Lys 751 Gln (rs13181), XRCC1 Arg399 Gln (rs25487) and XRCC3 Thr 241Met (rs861539) with the susceptibility of lung cancer in Saudi population. Nucleosides, Nucleotides & Nucleic Acids, pp.1-25. |
|
6. Rasheed, Z., Alhomaidan, H., Shariq, A., Alkhowailed, M., Alqossayir, F., Rasheed, N., Alkhamiss, A., Alghsham, R., Hershan, A., Alharbi, S. and Alsagaby, S., 2022. An Updated Analysis on the Risk Factors Associated with COVID-19 Transmission. Open Access Macedonian Journal of Medical Sciences, 10(E), pp.355-360. An Updated Analysis on the Risk Factors Associated with COVID-19 Transmission |
|
7. Anwar, S., DasGupta, D., Shafie, A., Alhumaydhi, F.A., Alsagaby, S.A., Shahwan, M., Anjum, F., Al Abdulmonem, W., Sharaf, S.E. and Hassan, M.I., 2022. Implications of Tempol in Pyruvate Dehydrogenase Kinase 3 Targeted Anticancer therapeutics: Computational, Spectroscopic and Calorimetric Studies. Journal of Molecular Liquids, p.118581. |
|
8. Anjum, F., Sulaimani, M.N., Shafie, A., Mohammad, T., Ashraf, G.M., Bilgrami, A.L., Alhumaydhi, F.A., Alsagaby, S.A., Yadav, D.K. and Hassan, M.I., 2022. Bioactive phytoconstituents as potent inhibitors of casein kinase-2: dual implications in cancer and COVID-19 therapeutics. RSC Advances, 12(13), pp.7872-7882. |
|
9. Shamsi, A., Shahwan, M., Khan, M.S., Alhumaydhi, F.A., Alsagaby, S.A., Al Abdulmonem, W., Abdullaev, B. and Yadav, D.K., 2022. Mechanistic Insight into Binding of Huperzine A with Human Serum Albumin: Computational and Spectroscopic Approaches. Molecules, 27(3), p.797. |
|
10. Alsagaby, S.A., 2022. A comprehensive study on abnormalities associated with red blood cells in Saudi adult patients. International Journal of Health Sciences, 16(1), p.30. A comprehensive study on abnormalities associated with red blood cells in Saudi adult patients |
|
11. Mir, S.A., Firoz, A., Alaidarous, M., Alshehri, B., Dukhyil, A.A.B., Banawas, S., Alsagaby, S.A., Alturaiki, W., Bhat, G.A., Kashoo, F. and Abdel-Hadi, A.M., 2022. Identification of SARS-CoV-2 RNA-dependent RNA polymerase inhibitors from the major phytochemicals of Nigella sativa: An in silico approach. Saudi journal of biological sciences, 29(1), pp.394-401. |
|
12. bbas, S., Chang, D., Riaz, N., Maan, A.A., Khan, M.K.I., Ahmad, I., Alsagaby, S.A., El-Ghorab, A., Ali, M., Imran, M. and Ullah, A., 2021. In-vitro stress stability, digestibility and bioaccessibility of curcumin-loaded polymeric nanocapsules. Journal of Experimental Nanoscience, 16(1), pp.229-245. |
|
13. Khodeir, M.M., Shabana, H.A., Rasheed, Z., Alkhamiss, A.S., Khodeir, M., Alkhowailed, M.S., Alharbi, S., Alsoghair, M., Alsagaby, S.A. and Al Abdulmonem, W., 2021. COVID-19: Post-recovery long-term symptoms among patients in Saudi Arabia. PloS one, 16(12), p.e0260259. COVID-19: Post-recovery long-term symptoms among patients in Saudi Arabia |
|
14. Iqbal, D., Khan, M.S., Waiz, M., Rehman, M.T., Alaidarous, M., Jamal, A., Alothaim, A.S., AlAjmi, M.F., Alshehri, B.M., Banawas, S. and Alsaweed, M., Alsagaby, S.A., Wael Alturaiki. 2021. Exploring the Binding Pattern of Geraniol with Acetylcholinesterase through In Silico Docking, Molecular Dynamics Simulation, and In Vitro Enzyme Inhibition Kinetics Studies. Cells, 10(12), p.3533. |
|
15. Alturaiki, W., Mubarak, A., Mir, S.A., Afridi, A., Premanathan, M., Mickymaray, S., Vijayakumar, R., Alsagaby, S.A., Almalki, S.G., Alghofaili, F. and Alnemare, A.K., 2021. Plasma levels of BAFF and APRIL are elevated in patients with asthma in Saudi Arabia. Saudi journal of biological sciences, 28(12), pp.7455-7459. Plasma levels of BAFF and APRIL are elevated in patients with asthma in Saudi Arabia |
|
16. Mousa, A.M., Alhumaydhi, F.A., Abdellatif, A.A., Abdulmonem, W.A., AlKhowailed, M.S., Alsagaby, S.A., Al Rugaie, O., Alnuqaydan, A.M., Aljohani, A.S., Aljasir, M. and Alwashmi, A.S., 2021. Curcumin and ustekinumab cotherapy alleviates induced psoriasis in rats through their antioxidant, anti-inflammatory, and antiproliferative effects. Cutaneous and Ocular Toxicology, pp.1-10. |
|
17.Althwab, S.A., Ahmed, A.A., Rasheed, Z., Alkhowailed, M., Hershan, A., Alsagaby, S., Alblihed, M.A., Alaqeel, A., Alrehaili, J., Alhumaydhi, F.A. and Alkhamiss, A., 2021. ATP2B1 genotypes rs2070759 and rs2681472 polymorphisms and risk of hypertension in Saudi population. Nucleosides, Nucleotides & Nucleic Acids, 40(11), pp.1075-1089. ATP2B1 genotypes rs2070759 and rs2681472 polymorphisms and risk of hypertension in Saudi population |
|
18. Alsagaby, S.A., Aljouie, A., Alshammari, T.H., Mir, S.A., Alhumaydhi, F.A., Al Abdulmonem, W., Alshaalan, H., Alomaish, H., Daghistani, R., Alsehawi, A. and Alharbi, N.K., 2021. Haematological and radiological-based prognostic markers of COVID-19. Journal of Infection and Public Health, 14(11), pp.1650-1657. Haematological and radiological-based prognostic markers of COVID-19 |
|
19. Shamsi, A., Shahwan, M., Alhumaydhi, F.A., Alwashmi, A.S., Aljasir, M.A., Alsagaby, S.A., Al Abdulmonem, W., Hassan, M.I. and Islam, A., 2021. Spectroscopic, calorimetric and in silico insight into the molecular interactions of Memantine with human transferrin: Implications of Alzheimer's drugs. International Journal of Biological Macromolecules, 190, pp.660-666. |
|
20. Alhumaydhi, F.A., Aljasir, M.A., Aljohani, A.S., Alsagaby, S.A., Alwashmi, A.S., Shahwan, M., Hassan, M.I., Islam, A. and Shamsi, A., 2021. Probing the interaction of memantine, an important Alzheimer's drug, with human serum albumin: In silico and in vitro approach. Journal of Molecular Liquids, 340, p.116888. |
|
21. Al Abdulmonem, W., Rasheed, Z., Alsagaby, S.A., Aljohani, A.S., Alkhamiss, A.S. and Ahmed, A.A., 2021. Impact of ERCC2 Lys751Gln (rs13181), ERCC2 Asp312Asn (rs1799793) and XRCC1 Arg399Gln (rs25487) polymorphisms on the risk of prostate cancer among cases from the central region of Saudi Arabia. Gene Reports, 24, p.101278. |
|
22. Alqahtani, S.M., A Alsagaby, S., Mir, S.A., Alaidarous, M., Bin Dukhyil, A., Alshehri, B., Banawas, S., Alturaiki, W., Alharbi, N.K., Azad, T.A. and Al Abdulmonem, W., 2021, August. Seroprevalence of Viral Hepatitis B and C among Blood Donors in the Northern Region of Riyadh Province, Saudi Arabia. In Healthcare (Vol. 9, No. 8, p. 934). |
|
23. Hala, S., Ribeca, P., Aljami, H.A., Alsagaby, S.A., Qasim, I., Gilbert, S.C. and Alharbi, N.K., 2021. Transcriptomic Profiling of Dromedary Camels Immunised with a MERS Vaccine Candidate. Veterinary sciences, 8(8), p.156. Transcriptomic Profiling of Dromedary Camels Immunised with a MERS Vaccine Candidate |
|
24. Mousa, A.M., Almatroudi, A., Alwashmi, A.S., Al Abdulmonem, W., Aljohani, A.S., Alhumaydhi, F.A., Alsahli, M.A., Alrumaihi, F., Allemailem, K.S., Abdellatif, A.A. Khan, A., AlsagabyS.A., 2021. Thyme oil alleviates Ova-induced bronchial asthma through modulating Th2 cytokines, IgE, TSLP and ROS. Biomedicine & Pharmacotherapy, 140, p.111726. |
|
25. Suresh, M., Alfonisan, M., Alturaiki, W., Al Aboody, M.S., Alfaiz, F.A., Premanathan, M., Vijayakumar, R., Umamagheswari, K., Al Ghamdi, S. and Alsagaby, S.A., 2021. Investigations of bioactivity of Acalypha indica (L.), Centella asiatica (L.) and croton bonplandianus (Baill) against multidrug resistant bacteria and cancer cells. Journal of Herbal Medicine, 28, p.100359. |
|
26. Alsagaby, S.A., Brewis, I.A., Vijayakumar, R., Alhumaydhi, F.A., Alwashmi, A.S., Alharbi, N.K., Al Abdulmonem, W., Premanathan, M., Pratt, G., Fegan, C. and Pepper, C., 2021. Proteomics-based identification of cancer-associated proteins in chronic lymphocytic leukaemia. Electronic Journal of Biotechnology, 52, pp.1-12. Proteomics-based identification of cancer-associated proteins in chronic lymphocytic leukaemia |
|
27. Fareed, M.M., El-Esawi, M.A., El-Ballat, E.M., Batiha, G.E.S., Rauf, A., El-Demerdash, F.M., Alhumaydhi, F.A. and Alsagaby, S.A., 2021. In Silico Drug Screening Analysis against the Overexpression of PGAM1 Gene in Different Cancer Treatments. BioMed Research International, 2021. |
|
28. Khodeir, M.M., Shabana, H.A., Alkhamiss, A.S., Rasheed, Z., Alsoghair, M., Alsagaby, S.A., Khan, M.I., Fernández, N. and Al Abdulmonem, W., 2021. Early prediction keys for COVID-19 cases progression: A meta-analysis. Journal of infection and public health, 14(5), pp.561-569. Early prediction keys for COVID-19 cases progression: A meta-analysis |
|
29. Al-Baradie, R.S., Pu, S., Liu, D., Zeinolabediny, Y., Ferris, G., Sanfeli, C., Corpas, R., Garcia-Lara, E., Alsagaby, S.A., Alshehri, B.M. and Abdel-Hadi, A.M., 2021. Monomeric C-Reactive Protein Localized in the Cerebral Tissue of Damaged Vascular Brain Regions Is Associated With Neuro-Inflammation and Neurodegeneration-An Immunohistochemical Study. Frontiers in Immunology, 12, p.674. |
|
30. Alsagaby, S.A. and Alharbi, M.T., 2021. Cancer in Saudi Arabia (CSA): Web-Based Application to Study Cancer Data Among Saudis Using Waterfall Model. Journal of Multidisciplinary Healthcare, 14, p.2333. |
|
31. Alsagaby, S.A., 2021. Molecular Insights into the Potential of Extracellular Vesicles Released from Mesenchymal Stem Cells and Other Cells in the Therapy of Hematologic Malignancies. Stem Cells International, 2021. |
|
32. Alhumaydhi, F.A., Mackawy, A.M., Morgan, E.N., Al Abdulmonem, W., Alsagaby, S.A., Alwashmi, A.S., Aljohani, A.S., Aljasir, M.A., Almatroodi, S.A., Alruwetei, A.M. and Mousa, A.M., 2021. Potential role of folic acid in preventing male infertility associated with MTHFR gene C677T (rs1801133) polymorphism. All Life, 14(1), pp.730-743. |
|
33. Radwan, M.A.A., Alminderej, F.M., Premanathan, M., Alwashmi, A.S.S., Alhumaydhi, F.A., Alturaiki, W. and Alsagaby, S.A., 2020. Synthesis and evaluation of novel isoindoline-1, 3-dione derivatives as anticancer agents. Russian Journal of Bioorganic Chemistry, 46(6), pp.1087-1098. Synthesis and evaluation of novel isoindoline-1, 3-dione derivatives as anticancer agents |
|
34. Aljasim, T.A., Almasoud, A., Aljami, H.A., Alenazi, M.W., Alsagaby, S.A., Alsaleh, A.N. and Alharbi, N.K., 2020. High Rate of Circulating MERS-CoV in Dromedary Camels at Slaughterhouses in Riyadh, 2019. Viruses, 12(11), p.1215. High Rate of Circulating MERS-CoV in Dromedary Camels at Slaughterhouses in Riyadh, 2019 |
|
35. Alzahrani, F.A., Ahmed, F., Sharma, M., Rehan, M., Mahfuz, M., Baeshen, M.N., Hawsawi, Y., Almatrafi, A., Alsagaby, S.A., Kamal, M.A. and Warsi, M.K., 2020. Investigating the pathogenic SNPs in BLM helicase and their biological consequences by computational approach. Scientific reports, 10(1), pp.1-22. |
|
36. Alsagaby, S.A., 2020. Integration of proteomics and transcriptomics data sets identifies prognostic markers in chronic lymphocytic leukemia. Majmaah Journal of Health Sciences, 7(1), pp.1-1. |
|
37. Alsagaby, S.A., Vijayakumar, R., Premanathan, M., Mickymaray, S., Alturaiki, W., Al-Baradie, R.S., AlGhamdi, S., Aziz, M.A., Alhumaydhi, F.A., Alzahrani, F.A. and Alwashmi, A.S., 2020. Transcriptomics-based characterization of the toxicity of ZnO nanoparticles against chronic myeloid leukemia cells. International Journal of Nanomedicine, 15, p.7901. |
|
38. Ke, Y., Al Aboody, M.S., Alturaiki, W., Alsagaby, S.A., Alfaiz, F.A., Veeraraghavan, V.P. and Mickymaray, S., 2019. Photosynthesized gold nanoparticles from Catharanthus roseus induces caspase-mediated apoptosis in cervical cancer cells (HeLa). Artificial cells, nanomedicine, and biotechnology, 47(1), pp.1938-1946. |
|
39. Alsagaby, Suliman A. "Omics-based insights into therapy failure of pediatric B-lineage acute lymphoblastic leukemia." Oncology Reviews 13, no. 2 (2019). Omics-based insights into therapy failure of pediatric B-lineage acute lymphoblastic leukemia |
|
40. Alsagaby, S.A., 2019. Understanding the fundamentals of proteomics. Curr. Top. Pept. Protein Res, 20(3), p.25. |
|
41. Alsagaby, S.A. and Alhumaydhi, F.A., 2019. Proteomics insights into the pathology and prognosis of chronic lymphocytic leukemia. Saudi medical journal, 40(4), p.317. Proteomics insights into the pathology and prognosis of chronic lymphocytic leukemia |
|
42. Alsagaby, S.A., 2019. Transcriptomics-based validation of the relatedness of heterogeneous nuclear ribonucleoproteins to chronic lymphocytic leukemia as potential biomarkers of the disease aggressiveness. Saudi Medical Journal, 40(4), p.328. |
|
43. Vijayakumar, R., Sandle, T., Al-Aboody, M.S., AlFonaisan, M.K., Alturaiki, W., Mickymaray, S., Premanathan, M. and Alsagaby, S.A., 2018. Distribution of biocide resistant genes and biocides susceptibility in multidrug-resistant Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii—A first report from the Kingdom of Saudi Arabia. Journal of Infection and Public Health, 11(6), pp.812-816. |
|
44. Mickymaray, S., Alturaiki, W., Al-Aboody, M.S., Mariappan, P., Rajenderan, V., Alsagaby, S.A., Kalyanasundram, U. and Alarfajj, A.A., 2018. Anti-bacterial efficacy of bacteriocin produced by marine Bacillus subtilis against clinically important extended spectrum beta-lactamase strains and methicillin-resistant Staphylococcus aureus. International Journal of Medical Research & Health Sciences, 7(2), pp.75-83. |
|
45. Vijayakumar, R., Al-Aboody, M.S., Alturaiki, W., Alsagaby, S.A. and Tim, S., 2017. A study of airborne fungal allergens in sandstorm dust in Al-Zulfi, central region of Saudi Arabia. Journal of Environmental and Occupational Health, 6(1), pp.27-33. A study of airborne fungal allergens in sandstorm dust in Al-Zulfi, central region of Saudi Arabia |
|
46. Alsagaby, S.A., Brennan, P. and Pepper, C., 2016. Key molecular drivers of chronic lymphocytic leukemia. Clinical Lymphoma Myeloma and Leukemia, 16(11), pp.593-606. |
|
47. Vijayakumar, R., Aboody, M., AlFonaisan, M., Turaiki, W., Mickymaray, S., Mariappan, P., Alsagaby, S. and Sandle, T., 2016. Determination of minimum inhibitory concentrations of common biocides to multidrug-resistant gram-negative bacteria. Appl Med Res, 2(3), p.56. |
|
48. Govindaraju, K., Krishnamoorthy, K., Alsagaby, S.A., Singaravelu, G. and Premanathan, M., 2015. Green synthesis of silver nanoparticles for selective toxicity towards cancer cells. IET nanobiotechnology, 9(6), pp.325-330. Green synthesis of silver nanoparticles for selective toxicity towards cancer cells |
|
49. Alsagaby, S.A., Khanna, S., Hart, K.W., Pratt, G., Fegan, C., Pepper, C., Brewis, I.A. and Brennan, P., 2014. Proteomics-based strategies to identify proteins relevant to chronic lymphocytic leukemia. Journal of proteome research, 13(11), pp.5051-5062. Proteomics-based strategies to identify proteins relevant to chronic lymphocytic leukemia |
|
50. Alsagaby, S., I. Brewis, C. Pepper, C. Fegan, and P. Brennan. "Analysis of human B-cells with quantitative and sub-cellular proteomics." In Immunology, vol. 131, pp. 115-115. Analysis of human B-cells with quantitative and sub-cellular proteomics |